Submit a Protocol

Use PERA for all IRB applications

The Purdue HRPP/IRB utilizes the Purdue Excellence in Research (PERA) system for protocol submission.

Log in to PERA here.

Respond to IRB Revision Requests

Please respond promptly to the IRB with any requests for protocol revisions. The Cayuse system allows you to make edits in line with the protocol.

To address revisions, please follow the directions found here.

What can I do to speed up the processing of my submission?

The use of the Cayuse IRB system is anticipated to assist in the processing time of applications. Here are some additional tips to help researchers prepare their submission.

  • Be certain that all key personnel on the study have completed required training before submitting an IRB protocol.
  • Check recent updates and metrics to help anticipate the standard approval times.
  • Utilize the Purdue IRB Training and Tools page to find researcher guides and information you can use to develop your protocols. This will also give you the dates and times for upcoming in-person training sessions.
  • Contact us in advance. Our Chairs, Administrator, and Protocol Analysts will schedule virtual appointments to assist research teams. (Please see the Virtual Appointment Guidelines first.)

Last modified: Nov 19, 2025

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